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While these researchers' work appears rigorous from a technical standpoint, the lack of independent replication from other laboratories globally is a significant concern in scientific research

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Moreover, NAFLD patients, subjected to chronic lipid exposure, exhibit an inhibited lipophagy, whereas an acute addition of lipids to cells in vitro may enhance lipophagy, which might be an adaptive response

This theory (a.k.a

[PubMed: 11134121] 161